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KMID : 0371320030640020175
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Journal of the Korean Surgical Society
2003 Volume.64 No. 2 p.175 ~ p.179
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Gastrointestinal Autonomic Nerve Tumor (GANT) in Small Intestine
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Kim Jae-Il
Kim Han-Seong
Kim Ki-Hong
Park Young-Jin
Lee Myung-Soo
Kim Chul-Nam
Chang Surk-Hyo
Kim Ji-Il
Song Byung-Joo
Park Sung-Hye
Lee Woo-Jin
Chun Young-Bin
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Abstract
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Gastrointestinal autonomic nerve tumors (GANTs) represent a newly described entity, which are stromal tumors of the gastrointestinal tract, with neuronal differentiation. They are CD117 (c-kit) immunoreactive neoplasms and are often immunoreactive for S100 protein, synaptophysin, and CD34. Ultrastructural examination provides the definitive distinguishing features for diagnosing a GANT. The presence of electron-dense granules, or small vesicles, suggests the presence of postganglionic neurotransmitter vesicles. We experienced a 65-year-old female patient who complained of bloody diarrhea, and a 75-year-old male patient who complained of melena. They were diagnosed with a gastrointestinal stromal tumor by an abdominal CT and operation, and were diagnosed as GANT pathologically. Thus we report two cases of a gastrointestinal autonomic nerve tumor, with a review of the relevant literatures.
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KEYWORD
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GANT, Gastrointestinal autonomic nerve tumor (GANT), Small intestine
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